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Silodosin


Silodosin

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3 Lac / Kilogram

500 Gram (MOQ)

Business Type Manufacturer, Exporter, Supplier, Retailer, Trader, Distributor, Importer
Solubility Freely Soluble In Methanol And Ethanol (99.5%) And Very Slightly Soluble In Water.
Appearance Cream To White Crystalline Powder
Purity 99.5 %
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Product Details

Other Names
Silodosin, Silodosina.
CAS No.
160970-54-7
Application
Silodosin Used In The Treatment Of Enlarged Prostate.
Brand Name
Silodosin
Country of Origin
India
MF
C25H32F3N3O4
Description
Cream to white crystalline powder
Identification (By HPLC)
Retention time of major Peak in the chromatogram of the sample solution corresponds to that of the standard solution obtain in the test of assay by HPLC test.
Loss on Drying
Not more than 1.0 % w/w
Heavy metals
Not more than 20 ppm
Sulphated Ash
Not more than 0.2 % w/w
Assay by HPLC
Not less than 98.0 % w/w and Not more than 102.0 % w/w of C25H32F3N3O4
Number Of Flower
API
Product Code
NIKSAN/API/0111
Port
SAHAR AIR CARGO
Payment Terms
L/C, D/A, D/P, T/T, Other
Delivery Time
2-3 DAYS
Packaging Details
DOUBLE LDPE LINERS IN HDPE CARBOYS

Niksan Pharmaceutical is one of the leading manufacturer, supplier and exporterof the Silodosin. The best product manufactured by Niksan Pharmaceutical is Silodosin. We manufacture, supply and export best quality product of Silodosin API along withSilodosinformulations.

Niksan Pharmaceutical provides best quality product of Silodosin in all states of India like Kerala, Punjab, Rajasthan, Telangana, Bihar, Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Odisha, Madhya Pradesh, Andhra Pradesh, Haryana  and many other states.

Niksan Pharmaceutical is also manufacture and exports large quantity of Silodosin products in whole globe since many years in countries like Nepal, Taiwan, United Arab Emirates, Bangladesh, Iraq, Ireland, South Korea , Canada, Egypt, Indonesia, United States, Thailand, Philippines, Turkey, Nigeria, Australia, Germany, Malaysia, Vietnam, Spain, United Kingdom, Poland and many more countries.

Silodosin belongs to the alpha-blocker class of medicine. Silodosin used in the treatment of enlarged prostate.

ENLARGED PROSTATE: Enlarged prostate cause difficulty in urination, pain full urination ad also cause trouble in urine urgency.

Silodosin also called alpha-adrenoceptor antagonist which is used in the treatment of BPH.

SYNONYMS: Silodosin, Silodosina.

IUPAC NAME:1-(3-hydroxypropyl)-5-[(2R)-({2-[2-[2-(2, 2,2-

Trifluoroethoxy) phenoxy] ethyll} amino) propyl] indoline-

7-carboxamide

 

CAS NO: 160970-54-7

 

FORMULA: C25H32F3N3O4

MOLECULAR MASS: 495.534 g/mol

STORAGE CONDITIONS: Store in cool and dry place, away from light and heat. Do not put it in fridge or in bathroom. Keep away from children and pet.

HOW TO USE: Take Silodosin tablet/capsule orally with food one time per day. Take doctors’ advice before taking medicine. Silodosin comes in capsule so do not chew it or don’t open it.

 

 

HOW SILODOSIN WORKS: Silodosin blocks the alpha A1 receptors which located in urethra and bladder. By blocking these receptors Silodosin relaxes the smooth muscles and by this process the flow of urination improves.

PHARMACOKINETICS OF SILODOSIN: Normally Silodosin absorbed by the gut. The AUC and peak plasma level may effected by the food. The bio avaibility of Silodosin is 32%. The metabolism of Silodosin is done in liver. The half-life of Silodosin is approximately 13.3±8.07 hrs. The rout of elimination of Silodosin is renal 33.5% and by faecal 54.9%.

 

SIDE EFFECTS OF SILODOSIN: The side effects of Silodosin are ejaculation problem, fainting, headache, dizziness, light headedness. If you have side effect like fainting or weakness contact your doctor and take advice. There are some rare side effects like rash, allergy, and redness of skin, itching or trouble in breathing.

 

PRECAUTIONS OF SILODOSIN: Tell your pharmacist if you have any allergic reaction to the Silodosin. Also tell your doctor if you have any disease related to lung, heart, liver or kidney. Do not drive or use any machinery because Silodosin makes you dizzy. Take less amount of alcohol and also if you are using cannabis talk to your doctor about using it

CDSCO APPROVAL: Silodosin Capsules2mg/4mg/8mg approved by CDSCO in India in 23.06.2011

Silodosin Tablets 4mg approved by CDSCO in Indian in 10.04.2012

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

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