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Benidipine


Benidipine

Link Copied
55,000.00 - 65,000.00 / Kilogram
Business Type Manufacturer, Exporter, Supplier, Retailer
Brand Name BENIDIPINE
Color White
Application Manufacturing Units
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Product Details

Certification
CE Certified, ISI Certified
Grade
MEDICINE GRADE
CAS No.
105979-17-7
EINECS No.
Not Applicable
Purity
99.8 %
Type
Pharmaceutical Raw Material
Country of Origin
India
Identification BY IR
IR spectrum of sample should match with that of working standard.
Identification BY UV
UV absorption of the sample must be concordant with the standard spectrum.
Identification BY Chloride test
Should be complies
Specific optical rotation
Between -1° to +1°
Residue after Ignition
Not more than 0.2% w/w
Individual unknown Impurity by HPLC
Not more than 0.5%
Total Impurities by HPLC
Not more than 1.0%
Assay (on dried basis)
Not less than 99.0% w/w and Not more than 101.0% w/w
Melting Point
About 200 °C (with decomposition)
Description
Yellowish or yellow crystalline powder
Heavy Metals
Not more than 20 ppm
Loss on Drying
Not more than 0.5% w/w
Solubility
Very soluble in formic acid, Soluble in methanol, Sparingly soluble in ethanol (99.5) and Practically insoluble in water.
Product Code
NIKSAN/API/0014
Port
SAHAR AIR CARGO
Payment Terms
Other
Delivery Time
2-3 DAYS
Packaging Details
DOUBLE LDPE LINERS IN HDPE CARBOYS

 

Niksan Pharmaceutical is the largest manufacturer, Exporter sand supplier of Benidipine. Benidipine is a one of the most famous medicine invented by Japanese. Benidipine is first Launch in India by Niksan Pharmaceutical with manufacturing from first step. Nowadays Niksan Pharmaceutical is one of the leading manufacturer and exporter who manufacturing Benidipine as well as Intermediates of Benidipine.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Benidipine formulations in many countries for many years. Niksan pharmaceutical currently export Benidipine API and Formulation to countries like Japan, Myanmar, Shrilanka, UAE, Kenya, Vietnam, Australia, Saudi Arabia, United States, United Kingdom, China, and Korea and also in some European countries

 

 

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Benidipine to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, and Hyderabad Etc.

Benidipine is a new generation triple L-, T-, and N- type calcium channel blocker used as antihypertensive agent.

Benidipine is a new generation triple L-, T-, and N- type calcium channel blocker used as antihypertensive agent.

IUPAC NAME: 3-(3R)-1-benzylpiperidin-3-yl 5-methyl (4R)-2, 6-dimethyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate

FORMULATIONS IN MARKET:

Benidipine Hydrochloride tablets 4mg (film coated)

Benidipine Hydrochloride tablets 8mg (film coated)

Benidipine 4 MG tablets

Benidipine 8 MG tablets

Benidipine 4 MG +Telmisartan 80 MG tablets

Benidipine 4 MG +Telmisartan 40 MG tablets

Benidipine 4 MG +Metoprolol 25 MG tablet

Benidipine 4 MG +Metoprolol 50 MG tablets

Atenolol 50 MG +Benidipine 4 MG tablets

Benidipine 4 MG + Chlorthalidone 12.5 MG tablets

Benidipine 4 MG + Chlorthalidone 6.25 MG tablets

Benidipine 4 MG + Chlorthalidone 12.5 MG +Telmisartan 40 MG tablets

 

Benidipine 4 MG +Chlorthalidone 6.25 MG +Telmisartan 40 MG tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

 

 

 

CAS NO: 105979-17-7

 FORMULA: C28H31N3O6

 

MOLECULAR MASS: 505.571 g/mol

 

STORAGE: Store in room temperature.

Place it in cool and dry place.

APPLICATION: Benidipine is mostly use as antihypertensive agent. It also used in the Angina pectoris. The tablet is given when the chest pain occurs.

 

HOW TO USE:  Benidipine tablet taken orally with food. It is given 2-4mg daily.

When chest pain occurs take 4mg 2 times per day.

 

CONTRAINDICATIONS: Do not take Benidipine medicine in pregnancy and lactation period. Take your doctor’s advice before taking medicine.

 

PHARMACOKINETICS: Benidipine is rapidly absorbed after oral administration reaching a maximum concentration within 2 hours. Benidipine completely metabolize in liver. Excretion is done by faces; most of the drug is excreted by bile.

 

SIDE EFFECTS: Benidipine have side effects like hypersensitivity (rash, itching), sometimes musculoskeletal effects like redness, stiffing in shoulders are also shown. Benidipine also give effects on heart like chest pain, hot flushes.There are also some minor side effects are also there like nausea, vomiting, headache, insomnia, constipation. If it goes worse take advice to your doctor.

 

PRECAUTIONS: If you have liver problems kindly avoid taking the medicine. Benidipine causes blurred vision and drowsiness so kindly avoids driving, operating machinery and performing any hazardous activity. Biperiden cause drowsiness so kindly avoid alcohol when taken medicine.

 

CDSCO APPROVAL: Benidipine Hydrochloride tablets are approved by CDSCO in India in 12.08.1996.

 

 

 

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